Pathways of aromatic amino acids synthesis. Reactions denoted as numbers are catalyzed by following enzymes: (1) 2-dehydro-3-deoxyphosphoheptonate aldolase, (2) dehydroquinate synthase, (3) 3-dehydroquinate dehydratase, (4) shikimate-NADP oxidoreductase, (5) shikimate kinase, (6) 5-enolpyruvylshikimate-3-phosphate synthase, (7) chorismate synthase, (8) chorismate mutase, (9) prephenate dehydrogenase, (10) phenylalanine:2-oxoglutarate transaminases, (11) phenylalanine 4-monooxygenase, (12) anthranilate synthase, (13) anthranilate phosphoribosyltransferase, (14) phosphoribosylanthranilate isomerase, (15) indole-3-glycerolphosphate synthase, (16) tryptophan synthase.