Skip to main content
. Author manuscript; available in PMC: 2014 Jan 24.
Published in final edited form as: J Immunol. 2010 Dec 3;186(1):312–322. doi: 10.4049/jimmunol.1001989

FIGURE 6.

FIGURE 6

LAGE-1104–121–specific CD4+ T cell clones are Th cells. Proliferation of allogenic CFSE-labeled naive CD45RA+ T cells obtained from PBLs of healthy donors was assessed after 5 d stimulation with soluble anti-CD3 (0.1 µg/ml) and IL-2 (50 IU/ml) in the presence of autologous non-CD3+ APCsandeithertheLAGE-1104–121–specificCD4+ Tcellclone116/12 or the TRAG-3–specific Treg clone 62/3 as control. Flow cytometry histograms of CFSE dilution by naive T cells are displayed for different ratios of effector CD4+ T cell clones to responder CD4+ and CD8+ naive T cells (E:R).