Table 1.
Maternal, fetal, and childhood characteristics (n=1184). Values are numbers (percentages) unless stated otherwise
| Characteristics | Value |
|---|---|
| Maternal | |
| Median (90% range) age, years | 31.3 (22.7-38.1) |
| Mean (SD) height, cm | 168.8 (7.0) |
| Mean (SD) pre-pregnancy weight, kg | 66.9 (11.8) |
| Mean (SD) pre-pregnancy body mass index, kg/m2 | 23.4 (3.9) |
| Median (90% range) gestational age at intake, weeks | 12.4 (10.5-13.9) |
| Mean (SD) systolic blood pressure, mm Hg | 116.7 (12.4) |
| Mean (SD) diastolic blood pressure, mm Hg | 69.1 (9.4) |
| Nulliparous | 717/1179 |
| Education: | |
| Primary or secondary school | 507/1155 (43.9) |
| Higher education | 648/1155 (56.1) |
| Race/ethnicity: | |
| Dutch, other European | 855/1175 (72.8) |
| Non-European | 320/1175 (27.2) |
| Smoking habits: | |
| Non-smoker | 820/1060 (77.4) |
| Smoker | 240/1060 (22.6) |
| Folic acid supplement use: | |
| None | 119/949 (12.5) |
| First 10 weeks | 294/949 (31.0) |
| Preconception | 536/949 (56.5) |
| Fetal | |
| Median (90% range) gestational age at fetal crown to rump length measurement, weeks | 12.4 (11.0-13.9) |
| Mean (SD) first trimester fetal crown to rump length, cm | 61 (11) |
| Birth and infant | |
| Male sex | 575 (48.6) |
| Median (90% range) gestational age at birth, weeks | 40.1 (37.0-42.0) |
| Mean (SD) birth weight, g | 3456 (551) |
| Ever breast feeding: | |
| No | 80/1046 (7.6) |
| Yes | 966/1046 (92.4) |
| Mean (SD) breastfeeding duration, months | 5.3 (3.8) |
| Childhood | |
| Median (90% range) age at follow-up, years | 6.0 (5.7-6.8) |
| Mean (SD) height, cm | 119.0 (5.5) |
| Mean (SD) weight, kg | 22.8 (3.7) |
| Mean (SD) body mass index, kg/m2 | 16.1 (1.7) |
| Mean (SD) total fat mass, % | 24.6 (5.2) |
| Mean (SD) android fat mass, % | 3.8 (0.9) |
| Mean (SD) gynoid fat mass, % | 15.3 (1.6) |
| Mean (SD) android/gynoid fat mass ratio | 0.25 (0.1) |
| Mean (SD) systolic blood pressure, mm Hg | 102.6 (8.1) |
| Mean (SD) diastolic blood pressure, mm Hg | 60.7 (6.8) |
| Mean (SD) cholesterol, mmol/L | 4.2 (0.7) |
| Mean (SD) low density lipoprotein cholesterol, mmol/L | 2.4 (0.6) |
| Mean (SD) high density lipoprotein cholesterol, mmol/L | 1.3 (0.3) |
| Mean (SD) high density/low density lipoprotein cholesterol ratio | 0.6 (0.2) |
| Median (90% range) triglycerides, mmol/L | 1.0 (0.4-2.1) |
| Median (90% range) insulin, pmol/L | 118.2 (25.9-342.4) |
| Median (90% range) C peptide, nmol/L | 1.0 (0.4-1.9) |
| Cardiovascular risk factor clustering | 81/745 (10.9) |