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. Author manuscript; available in PMC: 2014 Dec 23.
Published in final edited form as: Angew Chem Int Ed Engl. 2013 Nov 12;52(52):13997–14000. doi: 10.1002/anie.201306394

Figure 3.

Figure 3

CEST images of phantoms at 37 °C on a MRI 4.7 T scanner with a pulse train comprised of five Gauss pulses at 12 μT for 1 s, interpulse delay of 200 μs at +/−135 ppm. All solutions contain 40.0 mM HEPES buffer, pH 7.0, 200 mM NaCl, 8.0 mM Co(III)/Co(II) complex . Image (I): 1) [Co(TPT)]3+; 2) [Co(TPT)]3+ and 0.25 eq. Na2S2O4; 3) [Co(TPT)]3+ and 0.38 eq. Na2S2O4; 4) [Co(TPT)]3+ and 0.50 eq Na2S2O ; 5) [Co(TPT)]3+ 4 and 0.75 eq. Na2S2O4; 6) [Co(TPT)]3+ and 1.0 eq. Na2S2O4; 7) [Co(TPT)]3+ and 1.25 eq. Na2S2O4; 8) [Co(TPT)]2+. Scale represents the percent loss of signal due to CEST. Chart (II) represents phantom image intensities (average of three experiments).