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. 2014 Feb;20(2):185–191. doi: 10.3201/eid2002.131126

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Electron micrographs of muscle biopsy tissue from a 66-year-old man (case-patient B) (A) and a 67-year-old man (case-patient A) (B,C) showing Anncaliia algerae. A) Early proliferative stage meronts with diplokaryotic nuclei (n) and vesiculotubular appendages (arrows) attached to the plasmalemma. Scale bar indicates 1 μm. B) Degenerate crenated sporoblast (sb) and a mature spore with visible coils of the polar tubule (arrows). Scale bar indicates 1 μm. C) Mature spore with 9 polar tubule coils in a single row, pale endospore, and a dense exospore. Scale bar indicates 500 nm.