Table 2. Antimicrobial drugs administered to patient with inhalational anthrax diagnosed on hospital day 3, Minnesota, USA, 2011*.
Antimicrobial drug | Dose | Route, frequency | Hospital and post-hospitalization days medication administered |
---|---|---|---|
Ceftriaxone | 2.0 g | IV, every 24 h | 1–4 |
Azithromycin | 500 mg | IV, every 24 h | 1–3 |
Ciprofloxacin | 400 mg | IV, every 12 h | 2–26 |
Meropenem | 1.0 g | IV, every 8 h | 3–4 |
Vancomycin | 2.0 g | IV, once | 3 |
Clindamycin | 900 mg | IV, every 8 h | 4–14 |
Rifampin | 300 mg | Enteral, every 12 h | 4–8 |
Meropenem | 1.0 g | IV, every 8 h | 8–22 |
Ciprofloxacin | 500 mg | Oral, every 12 h | 26; PH 1-35† |
*IV, intravenous; hospital day, number of days in hospital including day of admission; PH, post-hospitalization days. †IV medication was discontinued and oral medication was started on day of discharge (hospital day 26) and continued for 35 additional days to complete 60 days of therapy.