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Nedd4-family domain structure. Members of the mouse Nedd4-family of E3 ubiquitin ligases share structural features. Domains of Nedd4-family members include the C2 domain, two-fourth WW domains, and the HECT domain. The HECT-domain is the catalytic subunit of the protein. Domain organization of these murine proteins is based on the National Center for Biotechnology Information database (http://www.ncbi.nlm.nih.gov/)
