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. 2013 Aug 15;6(8):1146–1159. doi: 10.1111/eva.12092

Figure 4.

Figure 4

Stable heterogeneity. The change over time of the fraction of producers and of the average fitness of the tumor. At the stable mixed equilibrium, producers and nonproducers coexist, unless the initial fraction of producers is lower than an internal unstable equilibrium (here approximately 0.25). c = 0.02, h = 0.5, s = 20, d = 3.