Table 3.
Relationship between GST-π expression and chemosensitivity
| Drug | Chemosensitivity | Cases (n) |
GST-π expression |
χ 2 | P | |
|---|---|---|---|---|---|---|
| Positive(n) | Negative(n) | |||||
| HCPT |
Sensitive |
32 |
20 |
12 |
0.725 |
0.632 |
| Resistant |
43 |
29 |
14 |
|||
| CDDP |
Sensitive |
33 |
15 |
18 |
8.122 |
0.013 |
| Resistant |
42 |
34 |
8 |
|||
| 5-FU |
Sensitive |
38 |
21 |
17 |
6.128 |
0.027 |
| Resistant |
37 |
28 |
9 |
|||
| ADM |
Sensitive |
31 |
20 |
11 |
0.850 |
0.578 |
| Resistant |
44 |
29 |
15 |
|||
| MMC |
Sensitive |
28 |
14 |
14 |
5.783 |
0.036 |
| Resistant | 47 | 35 | 12 | |||