Skip to main content
. 2014 Jan 24;9(1):e86117. doi: 10.1371/journal.pone.0086117

Figure 2. UFL and FFL attenuate HFD+LPS-induced increase in gut permeability and serum endotoxin level.

Figure 2

(A) Following the termination of treatment schedule, the animals were fasted for 12 h with access to water ad libitum. Subsequently, 1.0 ml of lactulose-mannitol solution (containing 66 mg/ml lactulose and 50 mg/ml mannitol) was administered to the animals by oral gavage. After another 20 h of fasting, the urine samples were collected to determine the level of lactulose and mannitol as described in Materials and Methods section. The data are expressed as a ratio of lactulose to mannitol. (B) After the termination of experimental schedule, the blood was collected from the animals following which the serum endotoxin level was determined as described in Materials and Methods section. ## P<0.01, compared to the normal group; * P<0.05, ** P<0.01 compared to the HFD control group; $ P<0.05, $$ P<0.01, compared to the normal group; & P<0.05 compared to the LPS control group (n = 8).