Table 1. Association of BRAF mutation status with clinicopathological parameters.
Characteristic | Rate Mutant | Mutant | Wild type | p-value1 |
All patients | 38.7% | 169 | 268 | |
Gender | 0.844 | |||
Male | 39.3% | 90 | 139 | |
Female | 38.0% | 79 | 129 | |
Age | <0.001 | |||
<50 years | 53.4% | 70 | 61 | |
50–59 years | 39.3% | 42 | 65 | |
60–69 years | 35.7% | 41 | 74 | |
≥70 years | 19.0% | 16 | 68 | |
Ulceration | 0.338 | |||
Yes | 45.7% | 21 | 25 | |
No | 37.9% | 148 | 243 | |
Tumor thickness | 0.190 | |||
≤0.50 mm | 30.2% | 29 | 67 | |
0.51–0.75 mm | 33.0% | 30 | 61 | |
0.76–1.00 mm | 46.2% | 24 | 28 | |
1.01–2.00 mm | 43.8% | 60 | 77 | |
2.01–4.00 mm | 42.2% | 19 | 26 | |
>4.00 mm | 43.8% | 7 | 9 | |
Histological subtype | <0.001 | |||
SSM | 43.0% | 141 | 187 | |
NM | 57.7% | 15 | 11 | |
LMM | 5.8% | 3 | 49 | |
ALM | 30.0% | 9 | 21 | |
Clark level | 0.277 | |||
I–III | 36.2% | 88 | 155 | |
IV or V | 41.8% | 81 | 113 | |
Mitoses/mm2 | 0.038 | |||
<1 | 33.2% | 72 | 145 | |
≥1 | 43.0% | 93 | 123 |
p-values are results of Chi-square tests.