Skip to main content
. 2014 Jan 24;9(1):e86194. doi: 10.1371/journal.pone.0086194

Table 1. Association of BRAF mutation status with clinicopathological parameters.

Characteristic Rate Mutant Mutant Wild type p-value1
All patients 38.7% 169 268
Gender 0.844
Male 39.3% 90 139
Female 38.0% 79 129
Age <0.001
<50 years 53.4% 70 61
50–59 years 39.3% 42 65
60–69 years 35.7% 41 74
≥70 years 19.0% 16 68
Ulceration 0.338
Yes 45.7% 21 25
No 37.9% 148 243
Tumor thickness 0.190
≤0.50 mm 30.2% 29 67
0.51–0.75 mm 33.0% 30 61
0.76–1.00 mm 46.2% 24 28
1.01–2.00 mm 43.8% 60 77
2.01–4.00 mm 42.2% 19 26
>4.00 mm 43.8% 7 9
Histological subtype <0.001
SSM 43.0% 141 187
NM 57.7% 15 11
LMM 5.8% 3 49
ALM 30.0% 9 21
Clark level 0.277
I–III 36.2% 88 155
IV or V 41.8% 81 113
Mitoses/mm2 0.038
<1 33.2% 72 145
≥1 43.0% 93 123
1

p-values are results of Chi-square tests.