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. 2014 Jan 24;9(1):e86319. doi: 10.1371/journal.pone.0086319

Table 1. Summary of associations between 11 SNPs in miR-101 and breast cancer risk.

SNP Chr Position Location Allelesa Caseb Controlb Call rate MAFc HWEd OR(95% CI)e P valuee
N = 1064 N = 1073 (%) (case/control)
rs7536540 1p31.3 65,524,582 hsa-mir-101-1 G/C 338/528/197 351/510/211 97.94 0.434/0.435 0.291 0.998(0.881–1.131) 0.982
rs1011210 1p31.3 65,526,176 hsa-mir-101-1 A/G 405/516/133 442/466/159 97.19 0.371/0.367 0.048
rs555146 1p31.3 65,527,407 hsa-mir-101-1 C/A 838/205/20 832/218/23 97.94 0.115/0.123 0.064 0.930(0.772–1.121) 0.446
rs578481 1p31.3 65,528,755 hsa-mir-101-1 A/G 507/460/97 535/436/101 97.99 0.307/0.298 0.381 1.042(0.910–1.192) 0.552
rs705509 1p31.3 65,531,751 hsa-mir-101-1 G/A 326/512/216 339/510/220 97.33 0.448/0.444 0.293 1.034(0.914–1.171) 0.594
rs462480 9p24.1 4,850,436 hsa-mir-101-2 A/C 531/442/88 591/395/86 97.80 0.291/0.265 0.084 1.182(1.030–1.357) 0.017
rs17718377 9p24.1 4,854,472 hsa-mir-101-2 G/C 821/227/13 845/218/10 97.85 0.119/0.111 0.437 1.113(0.914–1.356) 0.287
rs4742051 9p24.1 4,858,997 hsa-mir-101-2 A/G 576/412/74 618/386/68 97.85 0.264/0.244 0.456 1.139(0.988–1.314) 0.074
rs1537146 9p24.1 4,859,303 hsa-mir-101-2 A/G 623/388/51 655/361/57 97.89 0.231/0.222 0.426 1.081(0.931–1.255) 0.308
rs10974820 9p24.1 4,859,872 hsa-mir-101-2 G/A 875/180/8 905/162/5 97.89 0.092/0.080 0.538 1.174(0.938–1.469) 0.162
rs1053872 9p24.1 4,860,643 hsa-mir-101-2 C/G 265/532/265 305/541/226 97.85 0.500/0.463 0.667 1.179(1.040–1.337) 0.010
a

Major/minor allele;

b

Major homozygote/heterozygote/rare homozygote between cases and controls;

c

Minor allele frequency (MAF);

d

P values for Hardy-Weiberger equilibrium (HWE) tests;

e

Logistic regression with adjustment for age, age at menarche and menopausal status in additive model.