Figure 1. RUNX3 protein expression in tumor adjacent normal prostate tissues and prostate cancer tissues.

A Representative immunohistochemical photographs were taken at different magnifications in tumor adjacent normal prostate tissue and prostate cancer tissues (Top panel ×100, bottom panel ×400). B Compared with that in the tumor adjacent normal prostate tissue, the overall expression level of RUNX3 in the prostate cancer tissues was significantly lower (P<0.01, χ² test). C Decreased RUNX3 expression was correlated with TNM stage (P<0.01, χ² test, comparing I-II versus III–IV).