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. 2014 Jan 24;9(1):e87119. doi: 10.1371/journal.pone.0087119

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© 2014 Howitt et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Bright field image of dopaminergic neurons in the substantia nigra of a PD brain. (B–D) Fluorescent labelling of α-synuclein and Ndfip1 from the bright field image shows deposits of α-synuclein which co-label with Ndfip1 in a dopaminergic neuron (arrow). Asterisk marks a dopaminergic neuron with neither α-synuclein nor Ndfip1 positive labelling. (E) Fluorescent labelling of Ndfip1 in a control brain. Scale bar: 25 µm.