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Response and remission rates at the end of treatment. Pooled ITT population; LOCF. *P<0.05, **P<0.01, ***P<0.001. Response is defined as a decrease of 50% or greater from baseline to end of treatment in MADRS or HAMD17 total score. Remission is defined as an end-of-treatment MADRS total score≤10 or HAMD17 score≤7. HAMD17, 17-item Hamilton Depression Rating Scale; ITT, intent-to-treat; LOCF, last observation carried forward; MADRS, Montgomery–Åsberg Depression Rating Scale.
