Table 4.
Intervention issues of top five medications
| Medication | Vancomycin | Famotidine | Ranitidine | Meropenem | Theophylline |
|---|---|---|---|---|---|
| Intervention Issue | |||||
| Clinical pharmacokinetic service | 201 (85.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 20 (47.6) |
| Dosage increment or dosing interval decrement | 5 (2.1) | 4 (6.5) | 2 (3.4) | 13 (22.8) | 5 (11.9) |
| Dosage decrement or dosing interval increment | 8 (3.4) | 42 (67.7) | 36 (62.1) | 32 (56.1) | 1 (2.4) |
| Medication form | 1 (0.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (2.4) |
| Dosing time or dose | 19 (8.1) | 4 (6.5) | 5 (8.6) | 8 (14.0) | 10 (23.8) |
| Dosing route | 1 (0.4) | 3 (4.8) | 1 (1.7) | 0 (0.0) | 1 (2.4) |
| Discontinuation of medication | 0 (0.0) | 3 (4.8) | 2 (3.4) | 0 (0.0) | 1 (2.4) |
| Medication change | 0 (0.0) | 1 (1.6) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| Adverse drug reaction | 1 (0.4) | 5 (8.1) | 11 (19.0) | 2 (3.5) | 1 (2.4) |
| Fluid compatibility | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (1.8) | 0 (0.0) |
| Drug interaction | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (1.8) | 1 (2.4) |
| Others | 0 (0.0) | 0 (0.0) | 1 (1.7)1 | 0 (0.0) | 1 (2.4) |
| Total | 236 (100.0) | 62 (100.0) | 58 (100.0) | 57 (100.0) | 42 (100.0) |
Values are expressed as the number (percentage).
1Drug Omission.
P-value < 0.001.