Fig. 3.

Progenitor divisions in the postnatal and adult brain. a Neural stem cells (NSCs) in the adult ventricular (V)-subventricular zone (SVZ) neurogenic niche extend contacts to blood vessels and the lateral ventricle (LV) and are surrounded by ependymal cells (ECs). NSC divisions produce transit amplifying progenitors (TAPs) and oligodendrocyte precursor cells (OPCs), which in turn divide to generate postmitotic progeny. b Postnatal cortical astrocytes undergo symmetric proliferative divisions. c In the white matter, adult OPCs divide either symmetrically or asymmetrically to self-renew and produce differentiated oligodendrocytes