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. 2013 Jun 15;71(4):575–597. doi: 10.1007/s00018-013-1386-1

Fig. 4.

Fig. 4

Defects in polarity, spindle orientation, or cell-fate specification disrupt asymmetric division and result in hyperproliferation and loss of differentiation of Drosophila neuroblasts. Serial allografting of asymmetry-defective, hyperproliferative neuroblasts leads to chromosomal abnormalities and aneuploidy