Table 2.
Piglet age at RNR | Post-TBI survival time | Anterior midline (%) | Posterior midline (%) | Anterior right (%) | Anterior left (%) | Posterior right (%) | Posterior left (%) | Whole cerebrum (%) |
---|---|---|---|---|---|---|---|---|
5-day-old | Sham | 0±0 | 0±0 | 0±0 | 0±0 | 0±0 | 0±0 | 0±0 |
3–8 h | 79±10** | 74±10** | 32±5** | 35±4** | 36±4** | 35±5** | 37±4** | |
1 day | 49±9** | 48±8** | 17±3** | 27±6** | 27±4** | 24±3** | 26±4** | |
3–4 days | 38±12* | 28±10*a | 14±6 | 9±3*a | 12±5a | 13±4*a | 13±5*a | |
5–6 days | 15±6*ab | 5±2ab | 8±3*a | 6±3a | 3±1*bc | 4±2a | 5±2*a | |
4-week-old | Sham | 0±0 | 0±0 | 0±0 | 0±0 | 0±0 | 0±0 | 0±0 |
3–8 h | 46±8** | 57±8** | 25±5** | 26±5** | 28±3** | 27±5** | 28±4** | |
1 day | 49±10** | 53±9** | 20±5** | 22±5** | 25±5** | 24±4** | 25±8** | |
3–4 days | 7±2* | 24±8 | 6±1* | 8±2 | 14±3* | 13±4 | 11±2* | |
5–6 days | 2±1a | 8±2*ab | 1±0a | 2±1 | 3±1ab | 4±2ab | 3±1ab |
Significantly higher than sham; *p<0.05; ** p<0.01
Significantly lower than 3–8 h survival time group in same age/region; p<0.05.
Significantly lower than 1 day survival time group in same age/region; p<0.05.
Significantly lower than 3–4 day survival time group in same age/region; p<0.05.
All values are mean±standard error of mean.
RNR, rapid non-impact rotational injury; TBI, traumatic brain injury.