Table 1. Ras Point Mutations in MM.
| First Author | N12 | N13 | N61 | K12 | K13 | K61 | Total |
|---|---|---|---|---|---|---|---|
| Neri, patients at diagnosis244 | 2 | 2 | 9 | 2 | 1 | 0 | 12/43 |
| Neri, patients at relapse244 | 0 | 1 | 3 | 2 | 0 | 0 | 6/13 |
| Matozaki247 | 2 | 3 | 2 | 4/13 | |||
| Portier246 | 4 | 1 | 4 | 3 | 0 | 3 | 14/30 |
| Tanaka245 | 1 | 2 | 2 | 0 | 0 | 0 | 5/10 |
| Paquette248 | 2 | 2/17 | |||||
| Corradini243 | 2 | 1 | 7 | 1 | 0 | 0 | 11/90 |
| Yasuga249 | 0 | 2 | 2/45 | ||||
| Liu250 | 6/129 | 5/129 | 50/346 | 16/139 | 7/139 | 63/160 | |
| Total | 17/373 | 15/328 | 81/607 | 24/325 | 8/325 | 3/186 | |
| 4.5% | 4.6% | 13.3% | 7.4% | 2.5% | 1.6% | 34% |
The number of mutations of N-ras codon 12 (N12), codon 13 (N13), and codon 61 (N61), and of K-ras codon 12 (K12), codon 13 (K13), and codon 61 (K61) detected in MM patients in various studies is summarized.