Table 1.
Imaging Modality | Resolution | Sensitivity [Moles/l] |
Imaging Agents | Cost | Clinical/ Animal Use |
---|---|---|---|---|---|
PET | 1-2 mm (microPET); 4-5 mm (clinical PET) |
~10−11-10− 12 |
FDG, FLT, choline, acetate, nitroimidazole, antibody and antibody fragments |
High | Yes/Yes |
CT | 15-200 m | ~10−4 | Iodine Barium |
High | Yes/bone and lung imaging |
MRI | 10-100 m | ~10−3-10−5 | Gadolinium (+3), iron oxide particles, manganese oxide |
High | Yes/Yes |
Ultrasound | >40 m | a single bubble |
Contrast microbubles | Low | Yes/Yes |
Bioluminescence
Fluorescence |
several mm 2-3 mm |
~10−15 | Fluorescent molecules and dyes, targeted nanoparticles |
Low | No/Yes |