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In vivo experiment results for the reciprocating pump system showing acute delivery of drug. Drug supply was introduced to the system at t=0 in both experiments and again at t=150 minutes in Experiment B only. For Experiment A, the mean volume for each infuse cycle was 0.64 µL respectively at a period of 3 minutes. For Experiment B, these values were 1.18 µL at a period of 3–4 minutes.
