Table 1.

Density and number of keratocytes determined by histologic methods in corneas with Fuchs’ dystrophy and normal corneas.

Stromal Depth (%stromal thickness	Keratocyte Density (cells/mm3)			Number of Keratocytes*
	Fuchs’ (11 eyes)	Normal (3 eyes)	P‡	Fuchs’ (11 eyes)	Normal (5 eyes)	P‡
Full-thickness stroma	23,872 ± 3,340	33,376 ± 2,430	<0.001	12,215 ± 1,394	15,628 ± 710	<0.001
By stromal layer:
0–10% (anterior)	13,295 ± 5,359	42,747 ± 13,555	<0.001	682 ± 274	1,858 ± 404	<0.001
11–33%	22,121 ± 3,546	31,345 ± 3,050	<0.001	2,608 ± 402	3,297 ± 357	0.03
34–66%	25,886 ± 4,707	31,026 ± 2,006	0.99	4,361 ± 612	5,082 ± 431	0.17
67–90%	25,611 ± 4,542	32,906 ± 1,155	<0.001	3,143 ± 479	3,636 ± 420	0.34
91–100% (posterior)	27,655 ± 5,608	37,562 ± 2,735	<0.001	1,421 ± 300	1,752 ± 163	0.19

Mean ± standard deviation.

^*Absolute number of cells in a section of stroma with frontal area of 1 mm²