Common Class I transposons include LTR retrotransposons, which generally encode a capsid protein (GAG), protease (PRO), reverse transcriptase (RT), RNaseH (RH), and integrase (INT). By contrast, LINEs typically contain two open reading frames, one of unknown function and one that encodes endonuclease and reverse transcriptase activities. SINEs are non-autonomous elements whose sequence features are recognized by transposon-derived proteins acting in trans. Most Class II elements are TIR transposons, which can mobilize either autonomously or non-autonomously. Blue rectangles indicate protein-coding regions.