Table 1.

Expression of E6, p53 and p21 proteins and HPV16 physical state in Non-SIL and LSIL

	Non-IL		LSIL
	n=50	%	n=51	%	P
Expression of E6
Negative	9	18.0	0	0.0	0.006a
Mild	27	54.0	31	60.8
Moderate	13	26.0	17	33.3
Intense	1	2.0	3	5.9
Expression of p53
Negative	29	58.0	34	66.7	0.369b
Positive	21	42.0	17	33.3
Expression of p21
Negative	41	82.0	45	88.2	0.378b
Positive	9	18.0	6	11.8
HPV16 Physical state
Episomal	13	26.0	8	15.7	0.357b
Integrated	11	22.0	10	19.6
Mixed	26	52.0	33	64.7

HPV human papillomavirus, SIL squamous intraepithelial lesion, LSIL low-grade squamous intraepithelial lesion.

^aFisher exact test.

^b Χ ².

Significant value is indicated in bold.