. 2014 Jan 27;4:3868. doi: 10.1038/srep03868

Table 1. The results of PT/INR, APTT, Fbg, TT, FVIII:C, and FIX:C measurements.

	Baseline	Temperature	2 h	4 h	6 h	8 h	12 h	24 h
PT (s)	11.9 ± 2.7	4°C	11.6 ± 2.6^*	11.6 ± 2.5^*	11.7 ± 2.5^*	11.7 ± 2.5^*	11.9 ± 2.5^*	12.7 ± 2.9^*
		25°C	11.5 ± 2.6^*	11.4 ± 2.5^*	11.4 ± 2.4^*	11.3 ± 2.4^*	11.4 ± 2.3^*	12.8 ± 3.0^*
INR	1.08 ± 0.25	4°C	1.05 ± 0.23^*	1.05 ± 0.23^*	1.06 ± 0.22^*	1.06 ± 0.23^*	1.08 ± 0.23^*	1.15 ± 0.26^*
		25°C	1.05 ± 0.23^*	1.04 ± 0.22^*	1.03 ± 0.21^*	1.03 ± 0.21^*	1.04 ± 0.21^*	1.16 ± 0.27^*
APTT (s)	28.3 ± 5.8	4°C	28.4 ± 6.0	29.1 ± 6.3^*	29.7 ± 6.6^*	29.7 ± 6.2^*	30.7 ± 6.7^*	33.4 ± 7.9^*
		25°C	28.2 ± 5.9	28.8 ± 6.1^*	29.5 ± 6.3^*	30.2 ± 6.4^*	32.0 ± 6.7^*	34.2 ± 7.6^*
TT (s)	17.4 ± 0.79	4°C	17.3 ± 0.8^*	17.2 ± 0.8^*	17.2 ± 0.8^*	17.1 ± 0.8^*	17.2 ± 0.8^*	17.5 ± 0.8^*
		25°C	17.4 ± 0.8^*	17.3 ± 0.8^*	17.2 ± 0.8^*	17.3 ± 0.8^*	17.2 ± 0.8^*	17.8 ± 0.9^*
Fbg (g/L)	2.74 ± 0.81	4°C	2.79 ± 0.85^*	2.82 ± 0.85^*	2.79 ± 0.83^*	2.82 ± 0.84^*	2.79 ± 0.84^*	2.81 ± 0.83^*
		25°C	2.76 ± 0.83^*	2.78 ± 0.83^*	2.77 ± 0.83^*	2.79 ± 0.83^*	2.78 ± 0.85^*	2.77 ± 0.82
FVIII:C (%)	141.8 ± 42.2	4°C	132.1 ± 40.0^*	121.1 ± 36.9^*	112.6 ± 35.3^*	109.6 ± 37.1^*	101.2 ± 33.8^*	79.4 ± 25.7^*
		25°C	133.4 ± 41.0^*	121.1 ± 37.0^*	108.5 ± 34.1^*	98.9 ± 33.3^*	83.5 ± 28.7^*	72.4 ± 22.9^*
FIX:C (%)	101.1 ± 22.7	4°C	97.4 ± 21.2	94.4 ± 20.5^*	91.8 ± 19.4^*	91.9 ± 20.4^*	89.1 ± 20.0^*	87.4 ± 17.8^*
		25°C	98.0 ± 22.0^*	94.3 ± 20.4^*	91.1 ± 19.5^*	89.6 ± 19.2^*	85.2 ± 17.7^*	84.8 ± 16.6^*

*, p < 0.05 compared with baseline results.

Abbreviations: APTT, activated partial thromboplastin time; Fbg, fibrinogen; PT, prothrombin time; INR, the international normalized ratio; TT, thrombin time; FVIII:C, factor VIII activity; and FIX:C, factor IX activity.