. 2014 Jan 27;4:3850. doi: 10.1038/srep03850

Table 4. The parameters of steady-state activation and inactivation of wild-type and SCN5A variants.

	WT	N592K (1776C>G)	A551T (1651G>A)	P1090L (3269C>T)
V_{0.5, act}	−36.3 ± 0.2	−33.1 ± 0.3**	−38.1 ± 0.2**	−36.8 ± 0.3
s_{, act}	4.1 ± 0.2	5.3 ± 0.6	3.2 ± 0.2*	4.5 ± 0.2
V_{0.5, inact}	−86.4 ± 0.7	−85.2 ± 0.9	−87.8 ± 0.9	−87.9 ± 0.7
s_{, inact}	−7.5 ± 0.6	−7 ± 0.8	−7.1 ± 0.8	−8.6 ± 0.6

WT: Wild type; V_{0.5, act} is the half-activation potential and s_{, act} is the slope of the activation curve. V_{0.5, inact} is the half-inactivation potential and s_{, inact} is the slope of the inactivation curve. Data are mean ± SEM and the asterisks indicate the statistical significances by One-way ANOVA with Bonferroni post-hoc test (**P < 0.01; *P < 0.05; n = 4 in wt and 3269C>T and n = 3 in 1776C>G and 1651G>A).