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. Author manuscript; available in PMC: 2015 Jan 15.
Published in final edited form as: Cancer Res. 2013 Dec 3;74(2):621–631. doi: 10.1158/0008-5472.CAN-13-1928

Figure 4. Wyeth-14,643 reduces NSCLC angiogenesis and endothelial Cyp2c44 expression.

Figure 4

(A, B) Frozen sections of lung tumors from the KrasLA2 mice indicated were stained with anti-mouse CD31 antibodies. Tumor vascularization was quantified as described in the Materials and Methods. The values are means ± SD of 10 tumors/group with 2 images/tumor analyzed. (C, D) Frozen sections of lung tumors from KrasLA2 mice in groups 2 and 3 (C) or groups 4–6 (D) were co-stained with anti-mouse CD31 and anti-mouse Cyp2c44 antibodies. Images were merged to visualize endothelial expression of Cyp2c44. T, tumor; V, vasculature.