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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Mol Cancer Ther. 2013 Nov 18;13(1):60–70. doi: 10.1158/1535-7163.MCT-13-0518

Figure 2.

Figure 2

Knockdown of p110α enhances lapatinib sensitivity of lapatinib-resistant cells. (a) BT474 LapR cells were transfected with siRNA followed by western blot 3 days later. (b) BT474 and UACC893 LapR cells were transfected with p110α or p110β siRNA and given DMSO or 1μM lapatinib the next day. MTT assay was performed 3 days later. Error bars, s.e.m. (*p < 0.01 by one-way ANOVA of lapatinib-treated groups.)