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. 2014 Jan 9;4(1):e004119. doi: 10.1136/bmjopen-2013-004119

Table 2.

Results of regression analyses for dementia diagnosis and antidementia drug prescriptions

Years Dementia diagnosis
Numbers of antidementia drug prescriptions
Cost of antidementia drugs compared with overall spending
Estimate* (95% CI) p Value Estimate† (95% CI) p Value Estimate‡ (95% CI) p Value
<0.001 <0.001 <0.001
2006 0.96 (0.53 to 0.97) No data available No data available
2007 0.98 (0.97 to 0.98) No data available No data available
2008 0.94 (0.93 to 0.95) 0.88 (0.84 to 0.92) −0.95 (−1.13 to −0.68)
2009 Reference year
2010 1.04 (1.03 to 1.05) 1.11 (1.06 to 1.16) 0.54 (0.27 to 0.81)
2011 1.12 (1.11 to 1.13) 1.24 (1.19 to 1.29) 2.26 (1.99 to 2.53)

*Estimates represent incidence rate ratio of dementia diagnosis relative to year 2009 obtained from negative binomial regression, offset against population at risk.

†Estimates represent incidence rate ratio of number of antidementia drug prescriptions relative to year 2009 obtained from negative binomial regression, offset against total number of prescriptions.

‡Estimates represent the mean difference in relative cost of dementia drug obtained by multilevel linear regression compared with 2009.