Table 2.
Baseline demographics and coagulation parameters
| Control (n=25) | TEG (n=25) | p-value | |
|---|---|---|---|
| Demographics | |||
| Male gender, N (%) | 19 (76%) | 17 (68%) | 0.4* |
| Age (years), Mean (SEM) | 40 (2.44) | 38 (2.87) | 0.67 |
| BMI (kg/m2), Mean (SEM) | 29.23 (1.30) | 28.37 (1.39) | 0.65 |
| Injury Severity | |||
| Injury Severity Score, Median (IQR) | 27 (16–36) | 27 (19–33) | 0.92# |
| APACHE, Median (IQR) | 20 (17–26) | 23 (17–26) | 0.99# |
| Lactate (mmol/L), Mean (SEM) | 3.59 (0.43) | 3.97 (0.32) | 0.47 |
| Base Deficit (mEq/L), Mean (SEM) | 7.336 (0.77) | 8.04 (0.76) | 0.52 |
| Hemoglobin (g/dL), Mean (SEM) | 9.00 (0.33) | 8.53 (0.25) | 0.26 |
| Coagulation Parameters | |||
| Platelet Count (109/L), Mean (SEM) | 139.16 (9.78) | 120.32 (8.20) | 0.15 |
| Fibrinogen (mg/dL), Mean (SEM) | 636.00 (39.60) | 562.64 (27.18) | 0.13 |
| Antithrombin III (%), Mean (SEM) | 72.45 (3.53) | 62.60 (3.64) | 0.06 |
| aPTT (sec), Mean (SEM) | 34.17 (1.65) | 35.53 (1.09) | 0.5 |
| INR, Mean (SEM) | 1.35 (0.07) | 1.34 (0.03) | 0.91 |
| Anti-Xa, Mean (SEM) | 0.09 (0.00) | 0.09 (0.01) | 0.33 |
| Kaolin TEG | |||
| SP (min), Mean (SEM) | 4.63 (0.35) | 4.13 (0.44) | 0.38 |
| R (min), Mean (SEM) | 5.31 (0.32) | 5.26 (0.31) | 0.9 |
| K (min), Mean (SEM) | 1.43 (0.06) | 1.51 (0.08) | 0.41 |
| Angle (degrees), Mean (SEM) | 68.54 (1.06) | 66.40 (1.82) | 0.31 |
| MA (mm), Mean (SEM) | 65.84 (1.35) | 64.37 (1.10) | 0.4 |
| G (dynes/cm2), Mean (SEM) | 10.26 (0.76) | 9.36 (0.49) | 0.32 |
| LY30 (%), Mean (SEM) | 0.01 (0.00) | 0.01 (0.00) | 0.76 |
*
X2 test
#
Wilcoxon nonparametric test
All other p values were from t test for continuous variables
APACHE Acute Physiology and Chronic Health Evaluation; SP, split point; R, reaction time; K, kinetic time; MA, maximum amplitude; G, clot strength; LY30, lysis 30 minutes following MA.