Table 4. Significant Transfac motifs in liver regulatory regions.
Motif | Raw score | P-value relative to | ||
---|---|---|---|---|
Human chrom. 20 | Human promoters | Human CpG islands | ||
V$HNF1_01 | 32 | 0 | 0 | 0 |
V$HNF1_C | 25.5 | 0 | 0 | 0 |
V$HNF3ALPHA_Q6 | 8.38 | 0.001 | 0.002 | 0 |
V$HNF4ALPHA_Q6 | 7.23 | 0.001 | 0 | 0.001 |
V$HNF4_01 | 5.77 | 0.003 | 0.001 | 0.002 |
V$HNF3B_01 | 5.76 | 0.001 | 0.004 | 0.003 |
V$COUP_01 | 4.9 | 0.004 | 0.002 | 0.002 |
*V$XFD3_01 | 4.05 | 0.004 | 0.004 | 0.009 |
V$POLY_C | 4.03 | 0.005 | 0.002 | 0.004 |
V$HNF6_Q6 | 3.66 | 0.001 | 0.001 | 0.005 |
V$AP1_Q2 | 3.46 | 0.01 | 0.006 | 0.004 |
V$IPF1_Q4 | 2.28 | 0.005 | 0.002 | 0.006 |
*V$MZF1_01 | –3.03 | 0.995 | 0.999 | 1 |
*V$SPZ1_01 | –3.78 | 1 | 1 | 1 |
V$AP2_Q6 | –4.03 | 0.996 | 1 | 1 |
V$MUSCLE_INI_B | –4.07 | 0.998 | 0.999 | 1 |
V$CACCC_Q6 | –4.29 | 0.992 | 0.994 | 0.999 |
V$MINI20_B | –4.31 | 1 | 1 | 1 |
V$MINI19_B | –4.34 | 0.999 | 1 | 1 |
*V$PAX4_01 | –4.66 | 0.997 | 0.997 | 0.999 |
*V$MAZR_01 | –6.07 | 0.998 | 1 | 1 |
Motifs indicated with an asterisk are derived from in vitro site selection experiments.