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. Author manuscript; available in PMC: 2014 Jan 27.
Published in final edited form as: Nat Genet. 2013 Jul 14;45(9):977–983. doi: 10.1038/ng.2701

Figure 1. APOBEC3B is upregulated in numerous cancer types.

Figure 1

Each data point represents one tumor or normal sample, and the Y-axis is log-transformed for better data visualization. Red, blue, and yellow horizontal lines indicate the median APOBEC3B/TBP value for each cancer type (Table 1), the median value for each set of normal tissue RNAseq data (Supplementary Table 1), and individual RT-qPCR data points, respectively. Asterisks indicate significant upregulation of APOBEC3B in the indicated tumor type relative to the corresponding normal tissues (p<0.0001 by Mann-Whitney U-test). P-values for negative or insignificant associations are not shown.