Table 1. Characteristics of the study cohort.
Continuous data are given as means±S.D., irrespective of distribution or skewness. P values, however, derive from a Student's t test or Mann–Whitney U test as appropriate. Comparison between categorical data was performed using Fisher's exact test. SBP, systolic blood pressure; DBP, diastolic blood pressure; TAG, triacylglycerol; CRP, C-reactive protein; HbA1c, glycosylated haemoglobin; ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin II type I receptor blocker. *With T2D compared with Without T2D; †CAD compared with controls.
| CAD patients | |||||
|---|---|---|---|---|---|
| Parameter | With T2D (n=23) | Without T2D (n=56) | P value* | Controls (n=19) | P value† |
| Age (years) | 65±11 | 65±9 | 0.961 | 44±19 | <0.001 |
| Sex (male/female) (n) | 20/3 | 45/11 | 0.747 | 8/11 | 0.001 |
| BMI (kg/m2) | 31.7±5.2 | 28.6±4.7 | 0.026 | 26.5±1.9 | 0.004 |
| SBP (mmHg) | 138±22 | 138±26 | 0.897 | 132±23 | 0.471 |
| DBP (mmHg) | 73±13 | 80±11 | 0.065 | 84±12 | 0.162 |
| Total cholesterol (mmol/l) | 3.95±1.10 | 4.11±0.99 | 0.542 | 4.96±0.99 | 0.029 |
| LDL-cholesterol (mmol/l) | 1.80±0.83 | 2.00±0.78 | 0.314 | 2.69±1.11 | 0.024 |
| HDL-cholesterol (mmol/l) | 1.11±0.22 | 1.17±0.27 | 0.366 | 1.72±0.30 | <0.001 |
| TAG (mmol/l) | 2.54±1.97 | 2.04±0.97 | 0.262 | 1.17±0.47 | 0.052 |
| CRP (mg/l) | 2.5±2.9 | 5.0±10.5 | 0.280 | 3.5±4.2 | 0.843 |
| HbA1c (%) | 7.2±1.3 | 5.6±0.4 | <0.001 | 5.4±0.2 | 0.111 |
| Active smoking (yes/no) (n) | 2/22 | 2/54 | 0.579 | 2/17 | 0.324 |
| ACEI/ARB (yes/no) (n) | 18/5 | 32/24 | 0.122 | 1/18 | <0.001 |
| Statin (yes/no) (n) | 21/2 | 53/3 | 0.625 | 2/17 | <0.001 |
| Metformin (yes/no) (n) | 10/13 | 0/56 | <0.001 | 0/19 | <0.001 |