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(a) Liver concentrations of curcumin following a single dose of curcumin microparticles. (b) Hepatic GST and COX-2 activities following a single dose of curcumin microparticles. GST and COX-2 activities were determined using commercial assay kits, whereas curcumin concentrations were quantified by LC–MS/MS. Data shown are mean ± SE, n=6. *p < 0.05.
