Table 3.
Association Between mRNA Expression and CDDP for Genes Within the GSs RNA Binding and Cytoskeletal Part
| Gene Set | Gene | Correlation between IC50 and mRNA levels | Association p value |
|---|---|---|---|
| RNA binding | HNRNPF | −0.283 | 1.34E-06 |
| RNASEH2A | −0.282 | 1.38E-06 | |
| SNRPD1 | −0.280 | 1.65E-06 | |
| DIS3L | −0.278 | 2.01E-06 | |
| HNRNPA3 | −0.276 | 2.49E-06 | |
| DAZAP1 | −0.273 | 3.08E-06 | |
| HNRNPD | −0.271 | 3.60E-06 | |
| THOC6 | −0.267 | 5.25E-06 | |
| LGTN | 0.265 | 6.33E-06 | |
| KHDRBS1 | −0.261 | 8.78E-06 | |
| Cytoskeletal part | CENPF | −0.327 | 1.75E-08 |
| CAMSAP1L1 | 0.315 | 5.98E-08 | |
| LMNB1 | −0.311 | 9.25E-08 | |
| FEZ1 | 0.308 | 1.29E-07 | |
| GABARAPL1 | 0.304 | 1.78E-07 | |
| KIF20A | −0.300 | 2.77E-07 | |
| IFNGR1 | 0.297 | 3.56E-07 | |
| TOP2A | −0.296 | 3.78E-07 | |
| KIF3B | 0.296 | 3.80E-07 | |
| MYL5 | 0.295 | 4.32E-07 | |
| FAM33A | −0.294 | 4.75E-07 | |
| HOOK1 | −0.294 | 4.83E-07 | |
| POLB | 0.294 | 4.83E-07 | |
| NUSAP1 | −0.291 | 6.06E-07 | |
| CDCA8 | −0.285 | 1.04E-06 | |
| BLOC1S2 | 0.284 | 1.20E-06 | |
| PRC1 | −0.284 | 1.21E-06 | |
| IFT20 | 0.284 | 1.23E-06 | |
| CDC25B | −0.278 | 1.97E-06 | |
| TUBA1A | 0.277 | 2.18E-06 | |
| TUBA4A | −0.271 | 3.84E-06 | |
| TPX2 | −0.268 | 4.85E-06 | |
| MCM3 | −0.264 | 6.82E-06 | |
| KIF4A | −0.261 | 8.31E-06 | |
| FGFR1OP | −0.261 | 8.40E-06 | |
| KIF15 | −0.260 | 9.21E-06 | |
| MYO6 | −0.260 | 9.30E-06 |
The genes in bold print were selected for the functional studies.