Table 2. Frequencies of stop codons and nucleotides in the positions adjacent to stop codons in orthologous genes.
| Human | Yeast | |||||
|---|---|---|---|---|---|---|
| Stop codons | Introns | Significance of difference | Stop codons | Intergenic regions | Significance of difference | |
| UGA | 0.50 | 0.37 | 1.0E–72 | 0.29 | 0.28 | 0.38 |
| cUGA | 0.37 | 0.23 | 1.5E–141 | ND | ND | ND |
| gUGA | 0.29 | 0.22 | 1.5E–141 | ND | ND | ND |
| UGAg | 0.40 | 0.29 | 1.19E–43 | ND | ND | ND |
| UAG | 0.23 | 0.28 | 1.0E–72 | 0.24 | 0.24 | 0.84 |
| cUAG | 0.37 | 0.23 | 4.13E–47 | ND | ND | ND |
| gUAG | 0.28 | 0.22 | 4.13E–47 | ND | ND | ND |
| UAA | 0.27 | 0.35 | 1.0E–72 | 0.47 | 0.49 | 0.33 |
| UAAg | ND | ND | ND | 0.26 | 0.15 | 3.6E–9 |