TABLE 1 .
Predicted Tat-transported proteins in H. pylori
| Proteina | N-terminal sequenceb | Description | Protein predicted by the following Tat signal prediction programc: |
||
|---|---|---|---|---|---|
| PRED-TAT | TATFIND | TatP | |||
| HP0407 | MSISRRSILTKIPIALASANVLKA | Biotin sulfoxide reductase (BisC) | Yes | No | No |
| HP0631 | MFYDEKKTYQKIEERLDIVRSFNAHNEHKNLQDEFKGAGISRRDLLKWAGMMSTALALPASFAPLTLKA | Hydrogenase small subunit (HydA) | Yes | Yes | No |
| HP0874 | MKRRDFIKTTTLGATGAVLGAQILQA | Catalase-associated protein (KapA) | Yes | Yes | Yes |
| HP1540 | MADIQRRDFLGMSLASVTAIGAIAASLVAMKKTWDPLPSVVSA | Ubiquinol cytochrome c oxidase, Rieske (FbcF) | Yes | Yes | Yes |
a
HP numbers refer to H. pylori strain 26695 (21).
b
The signal sequence with the twin-arginine motif (the two arginines shown in boldface type) [consensus sequence (S/T)RRXFLK] is shown up to the cleavage site predicted by PRED-TAT (29). Conserved amino acids found in the Tat consensus sequence are underlined.
c
Prediction programs used in this study are PRED-TAT (29), TATFIND (30), and TatP (31). The proteins that were predicted by the programs are shown in boldface type.