Table 2. Percent of patients with biomarker elevations during months 13- 48^*.

Biomarker Elevation, %	(N=855)
AFP ≥20 ng/ml	28.3%
AFP ≥50 ng/ml	13.0%
AFP ≥200 ng/ml	3.0%
AFP ≥20 & 2× mean prev yr, %	16.8%
AFP L3% ≥10%, %	9.6%
AFP ≥20 & AFP L3% ≥10%, %	5.3%
DCP ≥40 mAU/mL, % elevated	70.5%
DCP ≥90 mAU/mL, % elevated	28.0%
DCP ≥150 mAU/mL, % elevated	16.1%
DCP ≥90 & 2× mean prev yr, %	25.0%
AFP ≥20 & DCP ≥90, %	10.9%
AFP ≥20 & DCP ≥90 & AFP L3% ≥10%, %	3.0%

^*Percent of patients, cases and controls combined, with a biomarker above the specified limits at any one of the 12 study visits from month 13 to month 48 (0.5 to 3.5 years after randomization).