Table 1. 50% inhibitory concentrations (IC50) for wild type and mutant derivatives.
Etoposide (µg/ml) | Doxorubicin (µg/ml) | |
---|---|---|
WT | 40 | 5 |
H759P | 180 | 12 |
M762P | 100 | 8 |
T767P | 32 | 5 |
N770P | 150 | 7 |
Q773P | 28 | 5 |
N774P | 38 | 3 |
H759A | 230 | 5 |
Etoposide (µg/ml) | Doxorubicin (µg/ml) | |
---|---|---|
WT | 40 | 5 |
H759P | 180 | 12 |
M762P | 100 | 8 |
T767P | 32 | 5 |
N770P | 150 | 7 |
Q773P | 28 | 5 |
N774P | 38 | 3 |
H759A | 230 | 5 |