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A and B, time course of the effect of intrathecal injection of 0.1–2 μg of AP5 on the paw withdrawal threshold measured with von Frey filaments (A) and a pressure stimulus (B) in rats treated with FK506 (1.5 mg kg−1 day−1 for 7 days). n= 7–8 rats per group. *P < 0.05 compared with the respective baseline value (time 0).
