Table 2. Changes in neurocognitive functions between the first and the final follow-up evaluation.
| Baseline (N = 74)a | Final follow-up (N = 74)a | P value | ||
| Global Deficit Score and Domain Deficit Score | ||||
| Global Deficit Score | 43.5 (9.2) | 46.6 (9.0) | 0.001 | |
| Memory Domain Deficit Score | 47.7 (14.3) | 50.9 (11.3) | 0.07 | |
| Attention Domain Deficit Score | 47.6 (11.3) | 52.5 (10.2) | 0.001 | |
| Motor Skills Domain Deficit Score | 45.6 (14.6) | 47.5 (14.7) | 0.26 | |
| Executive function Domain Deficit Score | 42.8 (9.8) | 45.1 (11.0) | 0.06 | |
| Specific Neurocognitive Test t -Scores | ||||
| Rey Complex Figure Test | ||||
| Copy (N = 73) | 44.4 (9.0) | 43.3 (8.8) | 0.26 | |
| Immediate Recallb (N = 49) | 47.9 (12.7) | 52.3 (12.4) | 0.002 | |
| Delayed Recallb (N = 49) | 45.6 (14.1) | 51.1 (12.2) | <0.001 | |
| California Verbal Leaning Test | ||||
| Long Delay (N = 72) | 52.1 (11.9) | 53.5 (11.4) | 0.12 | |
| Short Delay (N = 71) | 51.5 (12.1) | 53.1 (11.4) | 0.08 | |
| Sum (N = 72) | 55.4 (11.3) | 57.9 (12.6) | 0.01 | |
| Grooved Peg Board Test | ||||
| Dominant Hand (N = 69) | 44.3 (11.8) | 45.0 (11.9) | 0.68 | |
| Non-Dominant Hand (N = 72) | 44.8 (10.0) | 46.1 (10.6) | 0.17 | |
| Wisconsin Card Sort Test (Perseverative Errors; N = 72) | 37.6 (9.1) | 38.4 (7.7) | 0.38 | |
| Trail Making Test part A (N = 73) | 50.1 (12.0) | 52.5 (12.7) | 0.15 | |
| Trail Making Test part B (N = 72) | 52.2 (11.6) | 53.9 (11.8) | 0.30 | |
| Verbal Fluency Test (N = 73) | 52.4 (10.8) | 52.9 (10.7) | 0.60 | |
| Iowa Gambling Task (N = 48) | 47.0 (11.2) | 50.8 (11.5) | 0.04 | |
Values are means (SD).
a Number of individuals per time point unless otherwise.
b Scores for Immediate and Delayed Recall were only included if the Copy Score was at least 40, so that memory function was assessed in a more reliable manner. Abbreviations: GDS = Global Deficit Score; DDS = Domain Deficit Score.