Table 2.
Retinopathy Status of Study Participants and Associated Median Histidine-Rich Protein 2 Levels
| Feature | Retinopathy-
Positive Participants |
Retinopathy-
Negative Participants |
Pa | ||
|---|---|---|---|---|---|
| No. | HRP2 Level, Median (IQR) | No. | HRP2 Level, Median (IQR) | ||
| At least 1 sign of retinopathy | 80 | 27 (3–32) | 190 | 0.6 (0.005–19) | <.0001 |
| Hemorrhages | 41 | 29 (22–34) | 190 | 0.6 (0.005–19) | <.0001 |
| Macular whitening | 21 | 31 (28–34) | 190 | 0.6 (0.005–19) | <.0001 |
| Papilledema | 24 | 31 (1–36) | 190 | 0.6 (0.005–19) | .0129 |
| Peripheral whitening | 15 | 30 (23–32) | 190 | 0.6 (0.005–19) | .0001 |
| Vessel color changes | 18 | 14 (0–30) | 190 | 0.6 (0.005–19) | .3640 |
Abbreviation: IQR, interquartile range.
a For the median difference in HRP2 level between the retinopathy-positive and retinopathy-negative groups. The retinopathy features are not mutually exclusive. HRP2 levels are arbitrary units per microlitre of plasma.