Table 1.
Serum titers of the immunized Ifnarko-CD46Ge mice against human lambda immunoglobulin chain in antigen-mediated ELISA. The titers were measured on day 32 (for the 6–8-old mice) or 4 weeks post immunization (for the other two experiments).
| Experiment | Immunization | Anti-lambda titer | Difference (in fold) |
|---|---|---|---|
| 6–8-Week old mice (day 32) | MV-lambda-NAP | 1:6400–1:102,400a (1:36,480)b | 19.78c (p = 0.013) |
| MV-lambda | 1:200–1:6400 (1:1844) | ||
| 10–12-Week old mice (4 weeks) | MV-lambda-NAP | 1:1600–1:25,600 (10,720) | 9.08 (p = 0.010) |
| MV-lambda | 1:100–1:1600 (1:1180) | ||
| 16-Week old mice (4 weeks) | MV-lambda-NAP | 1:6400–1:25,600 (1:16,000) | 6.21 (p < 0.001) |
| MV-lambda | 1:800–1:6400 (1:2578) |
a
ELISA titer range.
b
Mean antibody titer.
b
Difference in titers MV-lambda-NAP vs. MV-lambda immunized groups in fold with the p value.