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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Lifetime Data Anal. 2013 Jun 27;19(4):568–588. doi: 10.1007/s10985-013-9270-8

Table 4. Estimates (Est.) and 95% confidence intervals (CI) of prediction indices based on two risk models used for predict 10-year CVD risk among women in the Framingham offspring cohort.

Cohort NCC QNCC
Est. CI Est. CI Est. CI
Model 1
 TPRt(p = 0.15) 0.083 (0.001, 0.165) 0.076 (0.025, 0.128) 0.069 (−0.005, 0.143)
 FPRt(p = 0.15) 0.014 (−0.002, 0.030) 0.013 (0.004, 0.021) 0.011 (−0.004, 0.026)
 PCFt(0.2) 0.510 (0.458, 0.562) 0.502 (0.431, 0.573) 0.503 (0.443, 0.562)
 PNFt(0.85) 0.483 (0.427, 0.538) 0.478 (0.411, 0.545) 0.466 (0.406, 0.526)
 AUCt 0.752 (0.721, 0.783) 0.747 (0.705, 0.789) 0.744 (0.708, 0.780)
 Mean( Inline graphict|T ≤ t) 0.077 (0.055, 0.099) 0.074 (0.050, 0.097) 0.075 (0.052, 0.097)
 Mean( Inline graphict|T > t) 0.039 (0.030, 0.047) 0.039 (0.030, 0.048) 0.039 (0.030, 0.048)
 MRDt 0.039 (0.023, 0.055) 0.035 (0.017, 0.054) 0.036 (0.020, 0.053)
 TPR;(ρ) 0.734 (0.704, 0.764) 0.742 (0.703, 0.782) 0.718 (0.679, 0.757)
 FPR;(ρ) 0.359 (0.333, 0.385) 0.371 (0.332, 0.411) 0.353 (0.320, 0.386)
 AARDt 0.375 (0.326, 0.425) 0.371 (0.304, 0.438) 0.365 (0.306, 0.424)
 NBt(p) 0.015 (0.008, 0.023) 0.015 (0.007, 0.023) 0.015 (0.007, 0.023)
Model 2
 TPRt(p = 0.15) 0.155 (0.061, 0.248) 0.083 (−0.034, 0.201) 0.131 (0.066, 0.196)
 FPRt(p = 0.15) 0.024 (0.007, 0.042) 0.014 (−0.010, 0.038) 0.021 (0.011, 0.032)
 PCFt(0.2) 0.542 (0.493, 0.592) 0.553 (0.487, 0.619) 0.521 (0.461, 0.581)
 PNFt(0.85) 0.472 (0.416, 0.529) 0.499 (0.437, 0.561) 0.442 (0.385, 0.499)
AUCt 0.758 (0.729, 0.787) 0.768 (0.730, 0.805) 0.743 (0.708, 0.779)
 Mean( Inline graphict|T ≤ t) 0.086 (0.062, 0.110) 0.088 (0.059, 0.117) 0.080 (0.056, 0.104)
 Mean( Inline graphict|T > t) 0.038 (0.029, 0.047) 0.038 (0.029, 0.046) 0.038 (0.029, 0.047)
 MRDt 0.048 (0.030, 0.067) 0.051 (0.026, 0.075) 0.042 (0.023, 0.060)
 TPR;(ρ) 0.696 (0.669, 0.723) 0.722 (0.687, 0.758) 0.683 (0.645, 0.720)
 FPR;(ρ) 0.310 (0.282, 0.338) 0.318 (0.280, 0.356) 0.318 (0.284, 0.351)
 AARDt 0.386 (0.338, 0.434) 0.404 (0.343, 0.465) 0.365 (0.307, 0.424)
 NBt(p) 0.016 (0.009, 0.023) 0.016 (0.009, 0.024) 0.015 (0.008, 0.022)
Model 2-Model 1
 TPRt(p = 0.15) 0.071 (−0.045, 0.188) 0.051 (−0.101, 0.203) 0.062 (−0.031, 0.154)
 FPRt(p = 0.15) 0.011 (−0.012, 0.033) 0.008 (−0.022, 0.039) 0.011 (−0.006, 0.028)
 PCFt(0.2) 0.032 (−0.034, 0.098) 0.051 (−0.044, 0.146) 0.018 (−0.054, 0.091)
 PNFt(0.85) −0.010 (−0.083, 0.063) 0.021 (−0.070, 0.112) −0.024 (−0.092, 0.044)
AUCt 0.006 (−0.033, 0.046) 0.021 (−0.035, 0.077) 0.000 (−0.044, 0.044)
 Mean( Inline graphict|T ≤ t) 0.009 (−0.023, 0.041) 0.014 (−0.022, 0.051) 0.005 (−0.028, 0.039)
 Mean( Inline graphict|T > t) −0.001 (−0.013, 0.012) −0.001 (−0.013, 0.011) 0.000 (−0.013, 0.012)
 MRDt 0.010 (−0.014, 0.033) 0.015 (−0.015, 0.046) 0.006 (−0.019, 0.031)
 TPR;(ρ) −0.038 (−0.073, −0.004) −0.020 (−0.070, 0.030) -0.035 (−0.076, 0.005)
 FPR;(ρ) −0.049 (−0.082, −0.016) −0.053 (−0.102, −0.004) −0.035 (−0.073, 0.003)
 AARDt 0.011 (−0.052, 0.074) 0.033 (−0.057, 0.123) 0.000 (−0.070, 0.070)
 NBt(p) 0.000 (−0.010, 0.011) 0.001 (−0.009, 0.012) 0.000 (−0.011, 0.010)

Estimates are obtained under cohort, NCC and quota sampling NCC (QNCC) designs