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. 2014 Jan 27;9(1):e85843. doi: 10.1371/journal.pone.0085843

Table 1. Demographic and clinical data of TLE-HS and TLE-NL patients.

TLE-HS (n = 118) TLE-NL (n = 47) P value
Sex 74 (63%) female; 44 (37%) male 27 (57%) female; 20 (43%) male X 2, p = 0.531
Age (range) 46 years (17–73) 43 years (19–74) T-test, p = 0.228
Age of seizure onset (range) 12 years (0–50) 16 years (2–45) T-test, p = 0.004
Family history of epilepsy 40 (34%) 27 (57%) X 2, p = 0.006
FS/IPI 13(11%)/26(22%) 3(6%)/12(25%) X 2, p = 0.356/p = 0.650
SE 3 (2%) 1 (2%) Fischeŕs exact test, p = 0.858
Duration of epilepsy (range) 32 years (2–62) 23 years (3–50) T-test, p = 0.001
Time of active epilepsy (range) 28 years (2–62) 22 years (3–47) T-test, p = 0.008
Seizure frequency 31 (26%) infrequent seizures; 87 (74%) frequent seizures 16 (34%) infrequent seizures; 31 (66%) frequent seizures X 2, p = 0.381
Seizure remission 12 (10%) 10 (21%) X 2, p = 0.063
Laterality of epileptogenic zone 64 left (54%); 54 right (46%) 37 left (79%); 10 right (21%) X 2, p = 0.001
Number of patients with SGTCS in the previous year 14 (12%) 12 (25%) X 2, p = 0.03

TLE-HS: temporal lobe epilepsy with MRI signs of hippocampal sclerosis; TLE-NL: temporal lobe epilepsy with normal MRI; FS: febrile seizure; IPI: initial precipitating injury; SE: status epilepticus; SGTCS: secondary generalized tonic-clonic seizures.