Table 1. Demographic and clinical data of TLE-HS and TLE-NL patients.
TLE-HS (n = 118) | TLE-NL (n = 47) | P value | |
Sex | 74 (63%) female; 44 (37%) male | 27 (57%) female; 20 (43%) male | X 2, p = 0.531 |
Age (range) | 46 years (17–73) | 43 years (19–74) | T-test, p = 0.228 |
Age of seizure onset (range) | 12 years (0–50) | 16 years (2–45) | T-test, p = 0.004 |
Family history of epilepsy | 40 (34%) | 27 (57%) | X 2, p = 0.006 |
FS/IPI | 13(11%)/26(22%) | 3(6%)/12(25%) | X 2, p = 0.356/p = 0.650 |
SE | 3 (2%) | 1 (2%) | Fischeŕs exact test, p = 0.858 |
Duration of epilepsy (range) | 32 years (2–62) | 23 years (3–50) | T-test, p = 0.001 |
Time of active epilepsy (range) | 28 years (2–62) | 22 years (3–47) | T-test, p = 0.008 |
Seizure frequency | 31 (26%) infrequent seizures; 87 (74%) frequent seizures | 16 (34%) infrequent seizures; 31 (66%) frequent seizures | X 2, p = 0.381 |
Seizure remission | 12 (10%) | 10 (21%) | X 2, p = 0.063 |
Laterality of epileptogenic zone | 64 left (54%); 54 right (46%) | 37 left (79%); 10 right (21%) | X 2, p = 0.001 |
Number of patients with SGTCS in the previous year | 14 (12%) | 12 (25%) | X 2, p = 0.03 |
TLE-HS: temporal lobe epilepsy with MRI signs of hippocampal sclerosis; TLE-NL: temporal lobe epilepsy with normal MRI; FS: febrile seizure; IPI: initial precipitating injury; SE: status epilepticus; SGTCS: secondary generalized tonic-clonic seizures.