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. 2014 Jan 27;9(1):e85165. doi: 10.1371/journal.pone.0085165

Table 2. Enhanced lignan uptake rate mediated by glycoprotein SC-2.

Incubation time, (min) Schisandrin B Schisandrin B+SC-2a
Uptake (µM) Decay rate constant, k1(min−1) Uptake (µM) Decay rate constant, k2 (L•mmol−1 min−1)
0 47b - 46b -
5 54±2 0.0140b 58±2 2.016×10−5 b
15 68±3 0.0140 82±2** 2.016×10−5
30 76±3 0.0053 86±4* 2.269×10−6
60 82±3 0.0020 91±5 1.429×10−6
90b 86b 0.0013b 93b 5.865×10−7 b
120b 82b −00013b 89b −1.092×10−6 b
a

Dose of SC-2 (MW: 841 kDa): 1 mg/mL ( = 1.1891×10−3 mM) (* p<0.05; ** p<0.01).

b

Values obtained by extrapolation.