Table 4. Estimation of the parameters at status of pseudo equilibrium.
Parameter | Initial totalextracellular concentration | Extracellular concentration (mM) | Intracellularconcentration, Lsin (mM) |
[SC-2]a | 1 mg/mL (1.1891×10−3 mM) | 0.0 | 0.0 |
[Mouter] | [Mouter]>>[SC-2], hence [Mouter] | [Mouter]>>[SC-2], hence [Mouter] | - |
≈constant | ≈constant | ||
[SC-2-Mouter] | 1.1891×10−3 mM | 1.1891×10−3 mM | 0.0 |
Lsc: | C0 = 0.1 mM | - | (peak concentration)c |
Schisandrin B | C0 = 0.1 mM | C0m = 0.007 mM | CmA′ = 0.093 mM; |
Gomisin C | C0 = 0.1 mM | C0m = 0.081 mM | CmA′ = 0.019 mM; |
Deoxyschsandrin | C0 = 0.1 mM | C0m = 0.085 mM | CmA′ = 0.015 mM; |
Assume CmA′ | |||
≈CmA(Fig. 8) | |||
[SC-2-Mouter]-Ls | 1.1891×10−3 mM | 1.1891×10−3 mM | 0.0 |
CmE b , c: | - | - | - |
Schisandrin B | - | - | 0.005 mM |
Gomisin C | - | - | 0.005 mM |
Deoxyschsandrin | - | - | 0.005 mM |