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. 2014 Jan 27;9(1):e85165. doi: 10.1371/journal.pone.0085165

Table 4. Estimation of the parameters at status of pseudo equilibrium.

Parameter Initial totalextracellular concentration Extracellular concentration (mM) Intracellularconcentration, Lsin (mM)
[SC-2]a 1 mg/mL (1.1891×10−3 mM) 0.0 0.0
[Mouter] [Mouter]>>[SC-2], hence [Mouter] [Mouter]>>[SC-2], hence [Mouter] -
≈constant ≈constant
[SC-2-Mouter] 1.1891×10−3 mM 1.1891×10−3 mM 0.0
Lsc: C0 = 0.1 mM - (peak concentration)c
Schisandrin B C0 = 0.1 mM C0m = 0.007 mM CmA′ = 0.093 mM;
Gomisin C C0 = 0.1 mM C0m = 0.081 mM CmA′ = 0.019 mM;
Deoxyschsandrin C0 = 0.1 mM C0m = 0.085 mM CmA′ = 0.015 mM;
Assume CmA
≈CmA(Fig. 8)
[SC-2-Mouter]-Ls 1.1891×10−3 mM 1.1891×10−3 mM 0.0
CmE b , c: - - -
Schisandrin B - - 0.005 mM
Gomisin C - - 0.005 mM
Deoxyschsandrin - - 0.005 mM
a

SC-2: MW = 841 kDa. 1 mg/mL = 1.1891×10−3 mM.

b

CmE: estimated from Fig. 9.

c

Be referred to Text S1, Table 2 and Fig. 9.