Table 9. Factors associated with occurrence of drug use problems, drug interactions and other problems.
| Factors | Drug use problems (n = 20) | Drug interactions (n = 97) | Other problems (n = 11) | ||||||
| Yes | No | p-value | Yes | No | p-value | Yes | No | p-value | |
| Elderly | |||||||||
| Yes | 16 (80.0) | 193 (80.8) | 1.000b | 77 (79.4) | 132 (81.5) | 0.801a | 10 (90.9) | 199 (80.2) | 0.696b |
| No | 4 (20.0) | 46 (19.2) | 20 (20.6) | 30 (18.5) | 1 (9.1) | 49 (19.8) | |||
| Duration of hospitalization | |||||||||
| Yes | 7 (35.0) | 82 (34.3) | 1.000a | 40 (41.2) | 49 (30.2) | 0.095a | 5 (45.5) | 84 (33.9) | 0.519b |
| No | 13 (65.0) | 157 (65.7) | 57 (58.8) | 113 (69.8) | 6 (54.5) | 164 (66.1) | |||
| Polypharmacy | |||||||||
| Yes | 15 (75.0) | 177 (74.1) | 1.000a | 87 (89.7) | 105 (64.8) | <0.001a * | 8 (72.7) | 184 (74.2) | 1.000b |
| No | 5 (25.0) | 62 (25.9) | 10 (10.3) | 57 (35.2) | 3 (27.3) | 64 (25.8) | |||
| Multiple comorbidities | |||||||||
| Yes | 17 (85.0) | 210 (87.9) | 0.722b | 96 (99.0) | 131 (80.9) | <0.001a * | 8 (72.7) | 219 (88.3) | 0.142b |
| No | 3 (15.0) | 29 (12.1) | 1 (1.0) | 31 (19.1) | 3 (27.3) | 29 (11.7) | |||
| Cardiovascular disease | |||||||||
| Yes | 8 (40.0) | 69 (28.9) | 0.429a | 41 (42.3) | 36 (22.2) | 0.001a * | 3 (27.3) | 74 (29.8) | 1.000b |
| No | 12 (60.0) | 170 (71.1) | 56 (57.7) | 126 (77.8) | 8 (72.7) | 174 (70.2) | |||
| Diabetes mellitus | |||||||||
| Yes | 12 (60.0) | 104 (43.5) | 0.234a | 52 (53.6) | 64 (39.5) | 0.038a * | 5 (45.5) | 111 (44.8) | 1.000b |
| No | 8 (40.0) | 135 (56.5) | 45 (46.4) | 98 (60.5) | 6 (54.5) | 137 (55.2) | |||
| Hypertension | |||||||||
| Yes | 14 (70.0) | 163 (68.2) | 1.000a | 89 (91.8) | 88 (54.3) | <0.001a * | 8 (72.7) | 169 (68.1) | 1.000b |
| No | 6 (30.0) | 76 (31.8) | 8 (8.2) | 74 (45.7) | 3 (27.3) | 79 (31.9) | |||
| Renal impairment | |||||||||
| Yes | 2 (10.0) | 45 (18.8) | 0.545b | 21 (21.6) | 26 (16.0) | 0.334 | 3 (27.3) | 44 (17.7) | 0.425 |
| No | 18 (90.0) | 194 (81.2) | 76 (78.4) | 136 (84.0) | 8 (72.7) | 204 (82.3) | |||
a
Computed using Continuity Correction;
b
Computed using Fisher's Exact Test;
*
Statistically significant (p<0.05).