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. Author manuscript; available in PMC: 2014 Jan 27.
Published in final edited form as: Am J Surg Pathol. 2013 Sep;37(9):1349–1356. doi: 10.1097/PAS.0b013e318290427d

FIGURE 2.

FIGURE 2

A case with (A) extensive, strong p16 positivity by IHC and (B) p53 negativity by IHC. C, A case with negative p16 IHC; and (D) RNA ISH for E6/E7 mRNA in the same case showing punctate, granular positivity.